.. User Manual - bossdevice research documentation master file, created by
sphinx-quickstart on Fri Jul 9 21:52:50 2021.
You can adapt this file completely to your liking, but it should at least
contain the root `toctree` directive.
.. toctree::
:numbered:
:hidden:
1_Home
2_DownloadAndSetup
3_StartBESTToolboxApplication
4_DesignExperiment
5_HardwareConfiguration
6_MEPHotspotSearch
7_MEPThresholdHunting
8_MEPDoseResponseCurve
9_MEPMeasurement
10_rsEEGMeasurement
11_TEPMeasurement
12_rTMSIntervention
13_TUSIntervention
14_TMSfMRIMeasurement
14_ERPMeasurement
15_SensoryThresholdHunting
15_IssuesBugsRequests
16_Workshops
17_About Us
============================================
Introduction to BEST Toolbox
============================================
To facilitate objectivity, reliability, and reproducibility of non-invasive brain stimulation (NIBS) studies and to empower students, researchers, and clinicians alike to conduct state-of-the-art multimodal NIBS studies, an automated but yet flexible tool for data collection and analysis is needed.
**B**\rain **E**\lectrophysiological recording and **ST**\imulation (**BEST**\) Toolbox is an easy-to-use MATLAB-based open-source software with a powerful graphical user interface (GUI), which allows the user to flexibly design, run, analyze, and share multi-protocol/multi-session NIBS studies, involving transcranial magnetic, electric, and ultrasound stimulation (TMS, tES, TUS) in combination with EMG, EEG, and fMRI.
The BEST toolbox interfaces with a large variety of recording and stimulation devices to analyze data and set stimulation parameters on-the-fly, thereby enabling closed-loop protocols and real-time applications. Its growing functionality includes e.g., TMS motor hotspot search, automated motor threshold estimation, measurement of motor evoked potentials (MEP) and TMS-evoked EEG potentials (TEP), dose-response curves, paired-pulse and dual-coil TMS, rTMS interventions, real-time EEG-triggered stimulation, concurrent TMS-fMRI, etc.
Hardware Interfaces
=============================================
BEST Toolbox is currently optimized for bossdevice firmware relase 2017b |sync2brain| , a data processing and control system implemented as Simulink© Real-Time model on a high performance computer system receiving a digital real-time data stream from an EEG system such such as:
* NeurOne TESLA (Bittium, FL)
* actiCHamp Plus (BrainProducts, DE)
* CED 1400 (Power and Micro, currently only for EMG modality)
Additionaly a native implementation of following buffers is also part of the toolbox.
* FieldTrip Real-Time Buffer
You may consult developers of BEST Toolbox at github discussions forum for questions specific hardware interfaces.
Input Devices
---------------------------------------------
The bossdevice firmware release 2017b and FieldTrip real-time buffer in turn allows the BEST Toolbox to interface with a wide variety of hardware and streaming platforms. Including but not limited to followings:
* Java
* Python
* Arduino
* BCI2000 includes the FieldTripBuffer and the FieldTripBufferSource modules
* BrainVision
* NeurOne TESLA
* BrainStream
* ANT NeuroSDK
* Artinis Medical Systems (NIRS)
* BrainVision Recorder
* Biosemi
* CTF (MEG)
* Emotiv
* Neuromag/Elekta (MEG)
* Jinga-Hi (LFP/EEG)
* Micromed (ECoG)
* ModularEEG/OpenEEG
* Neuralynx (LFP)
* Neurosky ThinkCap
* OpenBCI
* TMSI
* TOBI
The details about implementation of FieldTrip real-time buffer can be found |fieldtrip_buffer|
Output Devices
----------------------------------------------
BEST Toolbox is integrated with |MAGIC toolbox| and |neuroFUS open source APIs| in order to control and interact directly with the TMS devices that accepts TTL input for triggering and features API to set the device parameters:
* MagVenture (TMS)
* MagStim (TMS)
* BiStim (TMS)
* Rapid (TMS)
* DuoMag (TMS)
* neuroFUS (TUS)
In addition, it can also trigger any stimulation devices that can receive a TTL input trigger.
.. |sync2brain| raw:: html
sync2brain.
.. |fieldtrip_buffer| raw:: html
here.
.. |MAGIC toolbox| raw:: html
MAGIC toolbox
.. |neuroFUS open source APIs| raw:: html
neuroFUS open source APIs